FASCIA AND THE INFLUENCE OF HORMONES
Caterina Fede and her associates hypothesized that hormones – namely estrogen and relaxin, for example – are possibly implicated in the sensitization of fascial nociceptors. These hormones are critical to remodeling of the extracellular matrix by constraining fibrosis and inflammation, both of which exert a major influence on the stiffness of fascia and on sensitization…